Article
Female-biased association of NOS2-c.1823C>T (rs2297518) with co-susceptibility to metabolic syndrome and asthma.
Canadian journal of physiology and pharmacology - 1 Apr 2023
Aftabi Younes, Gilani Neda, Ansarin Atefeh, Amiri-Sadeghan Amir, Bakhtiyari Nasim, Seyyedi Maryam, Faramarzi Elnaz, Sharifi Akbar, Ansarin Khalil, Seyedrezazadeh Ensiyeh
Abstract excerpt
The nitric oxide (NO) pathway contributes to the pathogeneses of metabolic syndrome (MetS) and asthma. NOS2 encodes inducible-NO synthase, which is an important enzyme of the pathway, and its variations could affect the risk of asthma and MetS and thereby co-susceptibility to them. This study aims to estimate the association of NOS2-c.1823C>T with risk of asthma, MetS, and asthma with MetS condition (ASMetS), and...
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