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Article

Clonal haematopoiesis and dysregulation of the immune system.

Nature reviews. Immunology - 1 Sept 2023

Belizaire Roger, Wong Waihay J, Robinette Michelle L, Ebert Benjamin L

Abstract excerpt

Age-related diseases are frequently linked to pathological immune dysfunction, including excessive inflammation, autoreactivity and immunodeficiency. Recent analyses of human genetic data have revealed that somatic mutations and mosaic chromosomal alterations in blood cells - a condition known as clonal haematopoiesis (CH) - are associated with ageing and pathological immune dysfunction. Indeed, large-scale...

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Identifiers

PMID: 36941354
DOI: 10.1038/s41577-023-00843-3
PMCID: PMC11140722

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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