Article
Clonal Hematopoiesis: Connecting Aging and Inflammation in Atherosclerosis.
Current atherosclerosis reports - 1 Mar 2023
Polizio Ariel H, Park Eunbee, Walsh Kenneth
Abstract excerpt
PURPOSE OF REVIEW: Clonal hematopoiesis (CH) is a prevalent condition that results from the acquisition of somatic mutations in hematopoietic stem cells. When these mutations occur in "driver" genes, they can potentially confer fitness advantages to the cell, leading to a clonal expansion. While most clonal expansions of mutant cells are generally considered to be asymptomatic since they do not impact overall...
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