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Article

Clonal haematopoiesis of emerging significance.

Pathology - 1 Apr 2021

Hammond Danielle, Loghavi Sanam

Abstract excerpt

Clonal haematopoiesis (CH) is a ubiquitous feature of aging and provides mechanistic insight into the inextricable relationship between chronic inflammation and age-related diseases. Although CH confers a cumulative risk of subsequent haematological malignancy, particularly myeloid neoplasms, that risk is heavily mutation- and context-specific. Individuals with mutations in DNA damage response pathway genes...

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Identifiers

PMID: 33685721
DOI: 10.1016/j.pathol.2021.02.005

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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