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Article

Clonal hematopoiesis and bone marrow inflammation.

Translational research : the journal of laboratory and clinical medicine - 1 May 2023

Xie Xinshu, Su Meng, Ren Kehan, Ma Xuezhen, Lv Zhiyi, Li Zhaofeng, Mei Yang, Ji Peng

Abstract excerpt

Clonal hematopoiesis (CH) occurs in hematopoietic stem cells with increased risks of progressing to hematologic malignancies. CH mutations are predominantly found in aged populations and correlate with an increased incidence of cardiovascular and other diseases. Increased lines of evidence demonstrate that CH mutations are closely related to the inflammatory bone marrow microenvironment. In this review, we...

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Identifiers

PMID: 36347490
DOI: 10.1016/j.trsl.2022.11.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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