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Article

COVID-19 and the Genetics of Inflammation.

Critical care medicine - 1 Jun 2023

Choudhri Yasmeen, Maslove David M, Rauh Michael J

Abstract excerpt

OBJECTIVE: Interindividual variability in the clinical progression of COVID-19 may be explained by host genetics. Emerging literature supports a potential inherited predisposition to severe forms of COVID-19. Demographic and inflammatory characteristics of COVID-19 suggest that acquired hematologic mutations leading to clonal hematopoiesis (CH) may further increase vulnerability to adverse sequelae. This review...

Topics

Humans
COVID-19
SARS-CoV-2
Genome-Wide Association Study
Inflammation
Genetic Predisposition to Disease

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 36939259
DOI: 10.1097/CCM.0000000000005843
PMCID: PMC10187540

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-36939259-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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