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Article

Do monogenic inborn errors of immunity cause susceptibility to severe COVID-19?

The Journal of clinical investigation - 15 Jul 2021

Cotsapas Chris, Saarela Janna, Farmer Jocelyn R, Scaria Vinod, Abraham Roshini S

Abstract excerpt

The SARS-CoV-2 virus, which causes COVID-19, has been associated globally with substantial morbidity and mortality. Numerous reports over the past year have described the clinical and immunological profiles of COVID-19 patients, and while some trends have emerged for risk stratification, they do not provide a complete picture. Therefore, efforts are ongoing to identify genetic susceptibility factors of severe...

Topics

COVID-19
Genetic Predisposition to Disease
Humans
Interferon Type I
SARS-CoV-2

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 34061775
DOI: 10.1172/JCI149459
PMCID: PMC8279660

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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