Article
The role of host genetics in susceptibility to severe viral infections in humans and insights into host genetics of severe COVID-19: A systematic review.
Virus research - 1 Nov 2020
Elhabyan Abdelazeem, Elyaacoub Saja, Sanad Ehab, Abukhadra Abdelwahab, Elhabyan Asmaa, Dinu Valentin
Abstract excerpt
BACKGROUND: Susceptibility to severe viral infections was reported to be associated with genetic variants in immune response genes using case reports and GWAS studies. SARS-CoV-2 is an emergent viral disease that caused millions of COVID-19 cases all over the world. Around 15 % of cases are severe and some of them are accompanied by dysregulated immune system and cytokine storm. There is increasing evidence that...
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