Article
Genetic determinants of severe COVID-19 in young Asian and Middle Eastern patients: a case series.
Scientific reports - 20 Nov 2023
Badla Beshr Abdulaziz, Hanifa Mohamed Samer, Jain Ruchi, Naofal Maha El, Halabi Nour, Yaslam Sawsan, Ramaswamy Sathishkumar, Taylor Alan, Alfalasi Roudha, Shenbagam Shruti, Khansaheb Hamda, Al Suwaidi Hanan, Nowotny Norbert, Popatia Rizwana, Al Khayat Abdulla, Alsheikh-Ali Alawi, Loney Tom, AlDabal Laila Mohamed, Abou Tayoun Ahmad
Abstract excerpt
Studies of genetic factors associated with severe COVID-19 in young adults have been limited in non-Caucasian populations. Here, we clinically characterize a case series of patients with COVID-19, who were otherwise healthy, young adults (N = 55; mean age 34.1 ± SD 5.0 years) from 16 Asian, Middle Eastern, and North African countries. Using whole exome sequencing, we identify rare, likely deleterious variants...
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