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Article

A theoretical framework of immune cell phenotypic classification and discovery.

Frontiers in immunology - 1 Jan 2023

Hu Yuzhe, Liu Chen, Han Wenling, Wang Pingzhang

Abstract excerpt

Immune cells are highly heterogeneous and show diverse phenotypes, but the underlying mechanism remains to be elucidated. In this study, we proposed a theoretical framework for immune cell phenotypic classification based on gene plasticity, which herein refers to expressional change or variability in response to conditions. The system contains two core points. One is that the functional subsets of immune cells...

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Identifiers

PMID: 36936975
DOI: 10.3389/fimmu.2023.1128423
PMCID: PMC10018129

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