Article

Unravelling Immune Cell Signatures: CIBERSORTx-assisted Construction of Signature Matrix from Single-Cell Data

2024-05-05

Abstract excerpt

The immune system’s intricate orchestration is pivotal in combating infections and diseases, often leaving discernible signatures within circulating blood cells. Peripheral blood mononuclear cells (PBMCs), comprising diverse immune cell populations, serve as crucial indicators of immune system status and its responses to various conditions, including cancer. While traditional bulk metrics pose challenges in dissec...

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Literature Corpus work: 8df7dc6c-df56-50cd-b11c-9f24d2ceb5a3
DOI: 10.1101/2024.05.05.592045

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