Article

Machine Learning Identifies Signatures of Macrophage Reactivity and Tolerance that Predict Disease Outcomes

2022-06-30

Abstract excerpt

Single-cell transcriptomic studies have greatly improved organ-specific insights into macrophage polarization states are essential for the initiation and resolution of inflammation in all tissues; however, such insights are yet to translate into therapies that can predictably alter macrophage fate. Using machine learning algorithms on human macrophages, here we reveal the continuum of polarization states that is s...

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Literature Corpus work: a93d7e20-75cc-52c1-accc-7b6df24f8db2
DOI: 10.1101/2022.06.27.497783

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