Article

Hierarchical cell-type identifier accurately distinguishes immune-cell subtypes enabling precise profiling of tissue microenvironment with single-cell RNA-sequencing

2022-07-29

Abstract excerpt

<h4> A bstract </h4> Single-cell RNA-seq enabled in-depth study on tissue micro-environment and immune-profiling, where a crucial step is to annotate cell identity. Immune cells play key roles in many diseases while their activities are hard to track due to diverse and highly variable nature. Existing cell-type identifiers had limited performance for this purpose. We present HiCAT, a hierarchical, marker-based...

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Literature Corpus work: d95a777b-0071-53a6-9273-56643b0de0e5
DOI: 10.1101/2022.07.27.501701

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