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Article

High-Throughput Sequencing of the Major Histocompatibility Complex following Targeted Sequence Capture.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2017

Pröll Johannes, Fischer Carina, Michelitsch Gabriele, Danzer Martin, Niklas Norbert

Abstract excerpt

The Human Major Histocompatibility Complex (MHC) is a highly polymorphic region full of immunoregulatory genes. The MHC codes for the human leukocyte antigens (HLA), proteins that present on the cellular surface and that are involved in self-non-self recognition. For matching donors and recipients for organ and stem-cell transplants it is important to know an individual's HLA haplotype determinable in this...

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PMID: 28138842
DOI: 10.1007/978-1-4939-6750-6_5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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