Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Human leukocyte antigen super-locus: nexus of genomic supergenes, SNPs, indels, transcripts, and haplotypes

21 Dec 2022

Abstract excerpt

The human Major Histocompatibility Complex (MHC) or Human Leukocyte Antigen (HLA) super-locus is a highly polymorphic genomic region that encodes more than 140 coding genes including the transplantation and immune regulatory molecules. It receives special attention for genetic investigation because of its important role in the regulation of innate and adaptive immune responses and its strong association with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Glycosylation and Glycoproteins Research
Share to Immune Cell Function and Interaction
Share to Monoclonal and Polyclonal Antibodies Research

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36543786
DOI: 10.1038/s41439-022-00226-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 17 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Human leukocyte antigen super-locus: nexus of genomic supergenes, SNPs, indels, transcripts, and haplotypesPMID 36543786Read ↗

Next-Generation Sequencing of the HLA locus: Methods and impacts on HLA typing, population genetics and disease association studies.Semantic proximity Read ↗

The HLA genomic loci map: expression, interaction, diversity and disease.Semantic proximity Read ↗

HLA Genetics for the Human Diseases.Semantic proximity Read ↗

Complete sequences of six major histocompatibility complex haplotypes, including all the major MHC class II structures.Semantic proximity Read ↗

Progressing towards the complete and thorough characterization of the HLA genes by NGS (or single-molecule DNA sequencing): Consequences, opportunities and challengesSemantic proximity Read ↗

Complete sequences of six Major Histocompatibility Complex haplotypes, including all the major <i>MHC class II</i> structuresSemantic proximity Read ↗

The impact of next-generation sequencing technologies on HLA research.Semantic proximity Read ↗

A high-resolution HLA and SNP haplotype map for disease association studies in the extended human MHC.Semantic proximity Read ↗

Structural variation shapes regulatory and evolutionary diversity at the HLA locusSemantic proximity Read ↗

A statistical genetics guide to identifying HLA alleles driving complex diseaseSemantic proximity Read ↗

Benchmarking freely available human leukocyte antigen typing algorithms across varying genes, coverages and typing resolutionsSemantic proximity Read ↗

High-Definition Genomic Analysis of HLA Genes Via Comprehensive HLA Allele Genotyping.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.