Article

A coarse-grained NADH redox model enables inference of subcellular metabolic fluxes from fluorescence lifetime imaging

2020-11-21

Abstract excerpt

Mitochondrial metabolism is of central importance to diverse aspects of cell and developmental biology. Defects in mitochondria are associated with many diseases, including cancer, neuropathology, and infertility. Our understanding of mitochondrial metabolism in situ and dysfunction in diseases are limited by the lack of techniques to measure mitochondrial metabolic fluxes with sufficient spatiotemporal resolutio...

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Identifiers and source

Literature Corpus work: 317701ca-ae4e-5c52-b379-ac86525cfeef
DOI: 10.1101/2020.11.20.392225

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