Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Defining the phenotypic spectrum of sporadic Creutzfeldt-Jakob disease MV2K: the kuru plaque type.

Brain : a journal of neurology - 1 Aug 2023

Baiardi Simone, Mammana Angela, Dellavalle Sofia, Rossi Marcello, Redaelli Veronica, Colaizzo Elisa, Di Fede Giuseppe, Ladogana Anna, Capellari Sabina, Parchi Piero

Abstract excerpt

The current classification of sporadic Creutzfeldt-Jakob disease identifies six major subtypes mainly defined by the combination of the genotype at polymorphic codon 129 (methionine/M or valine/V) of the prion protein gene and the type (1 or 2) of misfolded prion protein accumulating in the brain (e.g. MM1, MM2, MV1, MV2, etc.). Here, we systematically characterized the clinical and histo-molecular features...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain
Share to Creutzfeldt-Jakob Syndrome

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Neocortex

Share to Phenotype

Share to Prion Proteins

Share to Prions

Source

Open in PubMed Open full text

Identifiers

PMID: 36883639
DOI: 10.1093/brain/awad074
PMCID: PMC10393400

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Defining the phenotypic spectrum of sporadic Creutzfeldt-Jakob disease MV2K: the kuru plaque type.PMID 36883639Read ↗

Novel histotypes of sporadic Creutzfeldt-Jakob disease linked to 129MV genotype.Semantic proximity Read ↗

The Phenotypic Spectrum of Sporadic Creutzfeldt-Jakob Disease Cortical Subtype.Semantic proximity Read ↗

Deciphering the pathogenesis of sporadic Creutzfeldt-Jakob disease with codon 129 M/V and type 2 abnormal prion protein.Semantic proximity Read ↗

Atypical neuropathological sCJD-MM phenotype with abundant white matter Kuru-type plaques sparing the cerebellar cortex.Semantic proximity Read ↗

Incidence and spectrum of sporadic Creutzfeldt-Jakob disease variants with mixed phenotype and co-occurrence of PrPSc types: an updated classification.Semantic proximity Read ↗

Phenotypic diversity of genetic Creutzfeldt-Jakob disease: a histo-molecular-based classification.Semantic proximity Read ↗

Familial Creutzfeldt-Jakob disease with an R208H-129V haplotype and Kuru plaques.Semantic proximity Read ↗

Atypical sporadic CJD-MM phenotype with white matter kuru plaques associated with intranuclear inclusion body and argyrophilic grain disease.Semantic proximity Read ↗

A case of MV2K subtype of sporadic Creutzfeldt-Jakob disease with florid-like plaques: Similarities and differences to variant Creutzfeldt-Jakob disease.Semantic proximity Read ↗

A novel subtype of sporadic Creutzfeldt-Jakob disease with PRNP codon 129MM genotype and PrP plaques.Semantic proximity Read ↗

Review. The neuropathology of kuru and variant Creutzfeldt-Jakob disease.Semantic proximity Read ↗

Regional pattern of microgliosis in sporadic Creutzfeldt-Jakob disease in relation to phenotypic variants and disease progression.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.