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Article

Review. The neuropathology of kuru and variant Creutzfeldt-Jakob disease.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences - 27 Nov 2008

McLean Catriona A

Abstract excerpt

A comparison of the pathological profiles of two spongiform encephalopathies with a similar presumptive route of infection was performed. Archival kuru and recent variant Creutzfeldt-Jakob disease (vCJD) cases reveal distinct lesional differences, particularly with respect to prion protein, suggesting that the strain of agent is important in determining the phenotype. Genotype analysis of the polymorphism on...

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Identifiers

PMID: 18849282
DOI: 10.1098/rstb.2008.0086
PMCID: PMC2735511

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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