Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Phenotypic Spectrum of Sporadic Creutzfeldt-Jakob Disease Cortical Subtype.

Annals of neurology - 1 Apr 2026

Baiardi Simone, Vargiu Claudia Marina, Appleby Brian S, Barria Marcelo, Bentivenga Giuseppe Mario, Calì Ignazio, Carlà Benedetta, Cohen Mark, Giese Armin, Herms Jochen, Kortelainen Aino-Minerva, Ladogana Anna, Mammana Angela, Ritchie Diane, Windl Otto, Capellari Sabina, Parchi Piero

Abstract excerpt

OBJECTIVE: The objective of this study was to characterize the phenotypic spectrum of the rare sporadic Creutzfeldt-Jakob disease cortical subtype (sCJDMM/MV2C) in a large multicentric autopsy cohort. METHODS: We evaluated clinical histories, biofluid markers, brain diffusion-weighted (DW)-magnetic resonance imaging (MRI), and electroencephalogram (EEG) findings in 56 patients. The histomolecular assessment...

Topics

Humans
Creutzfeldt-Jakob Syndrome
Male
Female
Middle Aged
Aged
Phenotype
Electroencephalography
Cerebral Cortex
Aged, 80 and over

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Adult

Diffusion Magnetic Resonance Imaging

Prion Proteins

Brain

Cohort Studies

Source

Open in PubMed Open full text

Identifiers

PMID: 41424290
DOI: 10.1002/ana.78117
PMCID: PMC13011778

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Phenotypic Spectrum of Sporadic Creutzfeldt-Jakob Disease Cortical Subtype.PMID 41424290Read ↗

Defining the phenotypic spectrum of sporadic Creutzfeldt-Jakob disease MV2K: the kuru plaque type.Semantic proximity Read ↗

Novel histotypes of sporadic Creutzfeldt-Jakob disease linked to 129MV genotype.Semantic proximity Read ↗

Phenotypic diversity of genetic Creutzfeldt-Jakob disease: a histo-molecular-based classification.Semantic proximity Read ↗

MRI lesion profiles in sporadic Creutzfeldt-Jakob disease.Semantic proximity Read ↗

Clinical diagnosis of MM2-type sporadic Creutzfeldt-Jakob disease.Semantic proximity Read ↗

Deciphering the pathogenesis of sporadic Creutzfeldt-Jakob disease with codon 129 M/V and type 2 abnormal prion protein.Semantic proximity Read ↗

Subtype Diagnosis of Sporadic Creutzfeldt-Jakob Disease with Diffusion Magnetic Resonance Imaging.Semantic proximity Read ↗

Incidence and spectrum of sporadic Creutzfeldt-Jakob disease variants with mixed phenotype and co-occurrence of PrPSc types: an updated classification.Semantic proximity Read ↗

Two different clinical phenotypes of Creutzfeldt-Jakob disease with a M232R substitution.Semantic proximity Read ↗

Sporadic Creutzfeldt-Jakob disease in adults over 80 years: a 10-year review of United Kingdom surveillance.Semantic proximity Read ↗

Current clinical diagnosis in Creutzfeldt-Jakob disease: identification of uncommon variants.Semantic proximity Read ↗

EEG - Imaging Evolution of the MV2 Subtype of Sporadic Creutzfeldt-Jakob Disease During the two-Year Course of the Disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.