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Article

Genetic Variants in Metabolic Signaling Pathways and Their Interaction with Lifestyle Factors on Breast Cancer Risk: A Random Survival Forest Analysis.

Cancer prevention research (Philadelphia, Pa.) - 1 Jan 2018

Jung Su Yon, Papp Jeanette C, Sobel Eric M, Zhang Zuo-Feng

Abstract excerpt

Genetic variants in the insulin-like growth factor-I (IGF-I)/insulin resistance axis may interact with lifestyle factors, influencing postmenopausal breast cancer risk, but these interrelated pathways are not fully understood. In this study, we examined 54 single-nucleotide polymorphisms (SNP) in genes related to IGF-I/insulin phenotypes and signaling pathways and lifestyle factors in relation to postmenopausal...

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Source

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Identifiers

PMID: 29074537
DOI: 10.1158/1940-6207.CAPR-17-0143
PMCID: PMC5754228

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AKT1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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