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Article

C-Reactive Protein: The Most Familiar Stranger

1 Mar 2023

Abstract excerpt

C-reactive protein (CRP) is a highly conserved pentraxin with pattern recognition receptor-like activities. However, despite being used widely as a clinical marker of inflammation, the in vivo functions of CRP and its roles in health and disease remain largely unestablished. This is, to certain extent, due to the drastically different expression patterns of CRP in mice and rats, raising concerns about whether the...

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PMID: 36881905
DOI: 10.4049/jimmunol.2200831

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