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Article

Conformationally Altered C-Reactive Protein Capable of Binding to Atherogenic Lipoproteins Reduces Atherosclerosis.

Frontiers in immunology - 1 Jan 2020

Pathak Asmita, Singh Sanjay K, Thewke Douglas P, Agrawal Alok

Abstract excerpt

The aim of this study was to test the hypothesis that C-reactive protein (CRP) protects against the development of atherosclerosis and that a conformational alteration of wild-type CRP is necessary for CRP to do so. Atherosclerosis is an inflammatory cardiovascular disease and CRP is a plasma protein produced by the liver in inflammatory states. The co-localization of CRP and low-density lipoproteins (LDL) at...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32849641
DOI: 10.3389/fimmu.2020.01780
PMCID: PMC7431523

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