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C-reactive protein: structure, function, regulation, and role in clinical diseases

14 Jun 2024

Abstract excerpt

C-reactive protein (CRP) is a plasma protein that is evolutionarily conserved, found in both vertebrates and many invertebrates. It is a member of the pentraxin superfamily, characterized by its pentameric structure and calcium-dependent binding to ligands like phosphocholine (PC). In humans and various other species, the plasma concentration of this protein is markedly elevated during inflammatory conditions,...

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PMID: 38947332
DOI: 10.3389/fimmu.2024.1425168

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