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Biological significance of C-reactive protein, the ancient acute phase functionary

4 Oct 2023

Abstract excerpt

. The attention regarding the origin of CRP and its multifunctionality has gripped researchers for several decades. The reason can be traced to the integrated evolution of CRP in the animal kingdom. CRP has been unequivocally listed as a key indicator of infectious and inflammatory diseases including autoimmune diseases. The first occurrence of CRP in the evolutionary ladder appeared in arthropods followed by...

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PMID: 37860004
DOI: 10.3389/fimmu.2023.1238411

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