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Article

High-Sensitive C-Reactive Protein: Universal Prognostic and Causative Biomarker in Heart Disease?

1 Feb 2012

Abstract excerpt

C-reactive protein (CRP), a pentraxin protein, is an established marker of acute phase reactions. There is some experimental evidence that the CRP molecule could be causative in all stages of atherosclerotic disease starting from endothelial dysfunction, continuing to plaque formation and destabilization, and to atherothrombotic complications. However, each claim of causality has elicited a counterpoint argument,...

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PMID: 22296194
DOI: 10.2217/bmm.11.108

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