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Functional analysis of polymorphism haplotypes of MGMT in residents of high background radiation area.

Mutagenesis - 12 May 2023

Zhou Linqian, Zhang Sufen, Huang WeiXu, Zhang Lingyu, Cai Yashi, Ke Weiyi, Cai Lina, Zou Jianming, Chen Huifeng

Abstract excerpt

To investigate the distribution of polymorphisms and their frequent haplotypes in the regulatory region of MGMT in residents of high background radiation area (HBRA) and their impacts on transcriptional activity, we collected DNA samples from 83 healthy Chinese residents in HBRA and searched for genetic polymorphisms in the regulatory region of MGMT. Haplotypes were characterized by Haploview analysis....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36852768
DOI: 10.1093/mutage/gead001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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