Article
Investigation of DNA repair-related SNPs underlying susceptibility to papillary thyroid carcinoma reveals MGMT as a novel candidate gene in Belarusian children exposed to radiation.
BMC cancer - 12 May 2017
Lonjou Christine, Damiola Francesca, Moissonnier Monika, Durand Geoffroy, Malakhova Irina, Masyakin Vladimir, Le Calvez-Kelm Florence, Cardis Elisabeth, Byrnes Graham, Kesminiene Ausrele, Lesueur Fabienne
Abstract excerpt
BACKGROUND: Genetic factors may influence an individual's sensitivity to ionising radiation and therefore modify his/her risk of developing papillary thyroid carcinoma (PTC). Previously, we reported that common single nucleotide polymorphisms (SNPs) within the DNA damage recognition gene ATM contribute to PTC risk in Belarusian children exposed to fallout from the Chernobyl power plant accident. Here we explored...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.