Article
ATP2B4 regulatory genetic variants are associated with mild malaria.
Malaria journal - 27 Feb 2023
Thiam Alassane, Nisar Samia, Adjemout Mathieu, Gallardo Frederic, Ka Oumar, Mbengue Babacar, Diop Gora, Dieye Alioune, Marquet Sandrine, Rihet Pascal
Abstract excerpt
BACKGROUND: Genome-wide association studies have identified ATP2B4 as a severe malaria resistance gene. Recently, 8 potential causal regulatory variants have been shown to be associated with severe malaria. METHODS: Genotyping of rs10900585, rs11240734, rs1541252, rs1541253, rs1541254, , , and was performed in 154 unrelated individuals (79 controls and 75 mild malaria...