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Article

Aspirin Use and Risk of Alzheimer's Disease: A 2-Sample Mendelian Randomization Study.

Journal of Alzheimer's disease : JAD - 1 Jan 2023

Ding Pingjian, Gorenflo Maria P, Zhu Xiaofeng, Xu Rong

Abstract excerpt

BACKGROUND: Observational studies have shown inconsistent findings of the relationships between aspirin use and the risk of Alzheimer's disease (AD). OBJECTIVE: Since residual confounding and reverse causality were challenging issues inherent in observational studies, we conducted a 2-sample Mendelian randomization analysis (MR) to investigate whether aspirin use was causally associated with the risk of AD....

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Alzheimer Disease
Aspirin
Coronary Disease
Genome-Wide Association Study
Mendelian Randomization Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

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Identifiers

PMID: 36846997
DOI: 10.3233/JAD-220787
PMCID: PMC11220559

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