Using a two-sample mendelian randomization analysis to explore the relationship between physical activity and Alzheimer's disease.

doi:10.1038/s41598-022-17207-x

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Article

Using a two-sample mendelian randomization analysis to explore the relationship between physical activity and Alzheimer's disease.

Scientific reports - 28 Jul 2022

Zhang Bowen, Huang Xiaowen, Wang Xiliang, Chen Xiaorui, Zheng Caifang, Shao Weihao, Wang Gaili, Zhang Weidong

Abstract excerpt

Evidence from previous epidemiological studies on the effect of physical activity on the risk of Alzheimer's disease (AD) is conflicting. We performed a two-sample Mendelian randomization analysis to verify whether physical activity is causally associated with AD. This study used two-sample Mendelian randomization (MR) analysis to estimate the association between physical activity (including overall activity,...

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PMID: 35902670
DOI: 10.1038/s41598-022-17207-x
PMCID: PMC9334579

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