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Article

Causal relationship between aspirin use and age-related macular degeneration.

Eye (London, England) - 1 Aug 2026

Zhu Juanhua, Zeng Chenggong, Tang Rongsui, Lu Weiwei, Wang Shasha, Huang Lijuan, Xiong Zhen, Deng Aijun, Zhen Zijun, Chen Rongyuan, Li Xuri

Abstract excerpt

OBJECTIVE: Although increasing evidence suggests an association between aspirin use and age-related macular degeneration (AMD), the potential causal relationship between them remains controversial. This study aims to explore the causal genetic association and potential mediators between aspirin use and AMD using Mendelian randomisation (MR) analysis. METHODS: A bidirectional, two-sample, two-step MR analysis was...

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Share to Anti-Inflammatory Agents, Non-Steroidal
Share to Apolipoprotein A-I

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Cholesterol, LDL

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Share to Polymorphism, Single Nucleotide

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Source

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Identifiers

PMID: 42215633
DOI: 10.1038/s41433-026-04574-2
PMCID: PMC13462141

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APOA1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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