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Article

Association of regular glucosamine use with incident dementia: evidence from a longitudinal cohort and Mendelian randomization study.

BMC medicine - 29 Mar 2023

Zheng Jiazhen, Ni Can, Zhang Yingchai, Huang Jinghan, Hukportie Daniel Nyarko, Liang Buwen, Tang Shaojun

Abstract excerpt

BACKGROUND: Emerging data suggests the neuroprotective and anti-neuroinflammatory effects of glucosamine. We aimed to examine the association between regular glucosamine use and risk of incident dementia, including dementia subtypes. METHODS: We conducted large-scale observational and two-sample Mendelian randomization (MR) analyses. Participants in UK Biobank having accessible data for dementia incidence and who...

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Identifiers

PMID: 36978077
DOI: 10.1186/s12916-023-02816-8
PMCID: PMC10052856

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