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Genome‐wide methylomic regulation of multiscale gene networks in Alzheimer's disease

22 Feb 2023

Abstract excerpt

INTRODUCTION: Recent studies revealed the association of abnormal methylomic changes with Alzheimer's disease (AD) but there is a lack of systematic study of the impact of methylomic alterations over the molecular networks underlying AD. METHODS: We profiled genome-wide methylomic variations in the parahippocampal gyrus from 201 post mortem control, mild cognitive impaired, and AD brains. RESULTS: We identified...

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PMID: 36811307
DOI: 10.1002/alz.12969

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