Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Article

Genetic association of the rs17782313 polymorphism with antipsychotic-induced weight gain.

Psychopharmacology - 1 Apr 2023

Schreyer Korbinian Felix, Leucht Stefan, Heres Stephan, Steimer Werner

Abstract excerpt

RATIONALE: Weight gain is a frequent side effect of treatment with SGAs (second-generation antipsychotics) and a leading cause for nonadherence. Several candidate genes have been identified that could influence the amount of AIWG (antipsychotic-induced weight gain). The polymorphism rs17782313 near the MC4R (human melanocortin 4 receptor gene) was strongly associated with obesity in a large scale GWAS (genome...

Topics

Humans
Amisulpride
Antipsychotic Agents
Genome-Wide Association Study
Olanzapine
Polymorphism, Single Nucleotide
Weight Gain

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Open in PubMed Open full text

Identifiers

PMID: 36757449
DOI: 10.1007/s00213-023-06331-9
PMCID: PMC10006246

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic association of the rs17782313 polymorphism with antipsychotic-induced weight gain.PMID 36757449Read ↗

Association of the common MC4R rs17782313 polymorphism with antipsychotic-related weight gain.Semantic proximity Read ↗

A meta-analysis of potential genetic factors associated with antipsychotic-induced weight gain in adults with severe mental illness.Semantic proximity Read ↗

MC4R rs489693: a clinical risk factor for second generation antipsychotic-related weight gain?Semantic proximity Read ↗

Genetic association study between antipsychotic-induced weight gain and the melanocortin-4 receptor gene.Semantic proximity Read ↗

A new genetic locus for antipsychotic-induced weight gain: A genome-wide study of first-episode psychosis patients using amisulpride (from the OPTiMiSE cohort).Semantic proximity Read ↗

Association study of polymorphisms in leptin and leptin receptor genes with antipsychotic-induced body weight gain.Semantic proximity Read ↗

Association between common variants near the melanocortin 4 receptor gene and severe antipsychotic drug-induced weight gain.Semantic proximity Read ↗

Pharmacogenetics of antipsychotic-induced weight gain: review and clinical implications.Semantic proximity Read ↗

Association between the -2548G/A polymorphism of the leptin gene and antipsychotic-induced weight gain: Analysis of the CATIE sample and meta-analysis.Semantic proximity Read ↗

Investigation of melanocortin system gene variants in antipsychotic-induced weight gain.Semantic proximity Read ↗

Methylenetetrahydrofolate reductase (MTHFR) 677C/T polymorphism is associated with antipsychotic-induced weight gain in first-episode schizophrenia.Semantic proximity Read ↗

Antipsychotic induced weight gain: genetics, epigenetics, and biomarkers reviewed.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.