Article
A new genetic locus for antipsychotic-induced weight gain: A genome-wide study of first-episode psychosis patients using amisulpride (from the OPTiMiSE cohort).
Journal of psychopharmacology (Oxford, England) - 1 May 2020
Ter Hark Sophie E, Jamain Stéphane, Schijven Dick, Lin Bochao D, Bakker Mark K, Boland-Auge Anne, Deleuze Jean-François, Troudet Réjane, Malhotra Anil K, Gülöksüz Sinan, Vinkers Christiaan H, Ebdrup Bjørn H, Kahn René S, Leboyer Marion, Luykx Jurjen J
Abstract excerpt
BACKGROUND: Antipsychotic-induced weight gain is a common and debilitating side effect of antipsychotics. Although genome-wide association studies of antipsychotic-induced weight gain have been performed, few genome-wide loci have been discovered. Moreover, these genome-wide association studies have included a wide variety of antipsychotic compounds. AIMS: We aim to gain more insight in the genomic loci affecting...
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