Article
Association of the common MC4R rs17782313 polymorphism with antipsychotic-related weight gain.
Journal of clinical psychopharmacology - 1 Feb 2013
Czerwensky Fabian, Leucht Stefan, Steimer Werner
Abstract excerpt
Weight gain is a frequent adverse effect of many second-generation antipsychotic (SGA) drugs. Although a number of candidate gene studies have focused on SGA-related weight gain, a clinical benefit for pharmacotherapy has not been achieved as yet. Genome-wide association studies offer great potential of identifying novel candidate genes and help to complete the search for relevant polygenetic risk factors. A...
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