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Article

Role of the Gut-Brain Axis in the Shared Genetic Etiology Between Gastrointestinal Tract Diseases and Psychiatric Disorders: A Genome-Wide Pleiotropic Analysis.

JAMA psychiatry - 1 Apr 2023

Gong Weiming, Guo Ping, Li Yuanming, Liu Lu, Yan Ran, Liu Shuai, Wang Shukang, Xue Fuzhong, Zhou Xiang, Yuan Zhongshang

Abstract excerpt

Importance: Comorbidities and genetic correlations between gastrointestinal tract diseases and psychiatric disorders have been widely reported, with the gut-brain axis (GBA) hypothesized as a potential biological basis. However, the degree to which the shared genetic determinants are involved in these associations underlying the GBA is unclear. Objective: To investigate the shared genetic etiology between...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36753304
DOI: 10.1001/jamapsychiatry.2022.4974
PMCID: PMC9909581

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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