Article
Therapy-selected clonal hematopoiesis and its role in myeloid neoplasms.
Leukemia research - 1 Mar 2023
Jahn Jacob, Diamond Benjamin, Hsu Jeffrey, Montoya Skye, Totiger Tulasigeri M, Landgren Ola, Maura Francesco, Taylor Justin
Abstract excerpt
Therapy-related myeloid neoplasms (t-MN) account for approximately 10-15% of all myeloid neoplasms and are associated with poor prognosis. Genomic characterization of t-MN to date has been limited in comparison to the considerable sequencing efforts performed for de novo myeloid neoplasms. Until recently, targeted deep sequencing (TDS) or whole exome sequencing (WES) have been the primary technologies utilized...
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