Article
Preleukaemic clonal haemopoiesis and risk of therapy-related myeloid neoplasms: a case-control study.
The Lancet. Oncology - 1 Jan 2017
Takahashi Koichi, Wang Feng, Kantarjian Hagop, Doss Denaha, Khanna Kanhav, Thompson Erika, Zhao Li, Patel Keyur, Neelapu Sattva, Gumbs Curtis, Bueso-Ramos Carlos, DiNardo Courtney D, Colla Simona, Ravandi Farhad, Zhang Jianhua, Huang Xuelin, Wu Xifeng, Samaniego Felipe, Garcia-Manero Guillermo, Futreal P Andrew
Abstract excerpt
BACKGROUND: Therapy-related myeloid neoplasms are secondary malignancies that are often fatal, but their risk factors are not well understood. Evidence suggests that individuals with clonal haemopoiesis have increased risk of developing haematological malignancies. We aimed to identify whether patients with cancer who have clonal haemopoiesis are at an increased risk of developing therapy-related myeloid...
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