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Clonal Hematopoiesis and Solid Cancers

19 May 2025

Abstract excerpt

Clonal hematopoiesis refers to the expansion of hematopoietic stem cells harboring somatic mutations, a phenomenon increasingly recognized in aging populations. This review highlights the emerging relationship between clonal hematopoiesis and solid cancers, focusing on the prevalence and impact of clonal hematopoiesis-associated mutations such as DNMT3A, TET2, ASXL1, and TP53 in tumorigenesis. Key risk factors...

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Acute Myeloid Leukemia Research
Cancer Genomics and Diagnostics
Epigenetics and DNA Methylation

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 40384356
DOI: 10.1111/cas.70097

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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