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Article

The interplay of clonal hematopoiesis and cancer: Clinical implications in oncology.

Cancer treatment reviews - 1 Apr 2026

Tanguay M, Tagliamento M, Samaniego J, Besse B, Renneville A, Bernard E, Micol J-B

Abstract excerpt

Clonal hematopoiesis (CH) refers to the expansion of hematopoietic stem and progenitor cells carrying somatic mutations and is increasingly identified in oncology through cell-free DNA testing. Once regarded mostly as a precursor to myeloid neoplasms and a contributor to cardiovascular disease, CH is now recognized as a major determinant of clinical outcomes in patients with cancer. Specific anticancer agents...

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Identifiers

PMID: 41791906
DOI: 10.1016/j.ctrv.2026.103109

Genes

PPM1D
TP53

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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