Article
A heuristic algorithm solving the mutual-exclusivity-sorting problem.
Bioinformatics (Oxford, England) - 1 Jan 2023
Vinceti Alessandro, Trastulla Lucia, Perron Umberto, Raiconi Andrea, Iorio Francesco
Abstract excerpt
MOTIVATION: Binary (or Boolean) matrices provide a common effective data representation adopted in several domains of computational biology, especially for investigating cancer and other human diseases. For instance, they are used to summarize genetic aberrations-copy number alterations or mutations-observed in cancer patient cohorts, effectively highlighting combinatorial relations among them. One of these is...
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