Article
On the Sample Complexity of Cancer Pathways Identification.
Journal of computational biology : a journal of computational molecular cell biology - 1 Jan 2016
Vandin Fabio, Raphael Benjamin J, Upfal Eli
Abstract excerpt
Advances in DNA sequencing technologies have enabled large cancer sequencing studies, collecting somatic mutation data from a large number of cancer patients. One of the main goals of these studies is the identification of all cancer genes--genes associated with cancer. Its achievement is complicated by the extensive mutational heterogeneity of cancer, due to the fact that important mutations in cancer target...
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