HBV genotype-dependent association of HLA variants with the serodecline of HBsAg in chronic hepatitis B patients.

doi:10.1038/s41598-023-27570-y

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

HBV genotype-dependent association of HLA variants with the serodecline of HBsAg in chronic hepatitis B patients.

Scientific reports - 7 Jan 2023

Chu Yu-Ju, Yang Hwai-I, Hu Hui-Han, Liu Jessica, Lin Yu-Ling, Chang Chia-Ling, Luo Wen-Sheng, Jen Chin-Lan, Chen Chien-Jen

Abstract excerpt

Seroclearance of hepatitis B surface antigen (HBsAg) is regarded as the functional cure for chronic hepatitis B (CHB). The relationship between human leukocyte antigen (HLA) variants, hepatitis B virus genotype, and longitudinal HBsAg serodecline remains to be explored. A total of 1735 HBeAg-seronegative CHB patients with genotype B or C infection of the community-based REVEAL-HBV cohort were genotyped for rs1710...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hepatitis B

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hepatitis B, Chronic

Share to Hepatitis B e Antigens

Share to Hepatitis B Surface Antigens

Share to Hepatitis B virus

Share to Histocompatibility Antigens

Share to Histocompatibility Antigens Class II

Share to HLA Antigens

Source

Open in PubMed Open full text

Identifiers

PMID: 36611047
DOI: 10.1038/s41598-023-27570-y
PMCID: PMC9825396

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

HBV genotype-dependent association of HLA variants with the serodecline of HBsAg in chronic hepatitis B patients.PMID 36611047Read ↗

HBV genotype-dependent association of HLA Variants with the Serodecline of HBsAg in Chronic Hepatitis B Patients: a 14-year Follow-up StudySemantic proximity Read ↗

Genetic Determinants of Spontaneous Hepatitis B Surface Antigen Seroclearance and Its Associated Viral Markers.Semantic proximity Read ↗

Host genetic factors affecting spontaneous HBsAg seroclearance in chronic hepatitis B patients.Semantic proximity Read ↗

Identification of novel susceptibility loci associated with hepatitis B surface antigen seroclearance in chronic hepatitis B.Semantic proximity Read ↗

HLA-DP and IL28B polymorphisms: influence of host genome on hepatitis B surface antigen seroclearance in chronic hepatitis B.Semantic proximity Read ↗

Higher lifetime chance of spontaneous surface antigen loss in hepatitis B carriers with genotype C infection.Semantic proximity Read ↗

HLA-DP genes polymorphisms associate with hepatitis B surface antigen kinetics and seroclearance during nucleot(s)ide analogue therapy.Semantic proximity Read ↗

Longitudinal characterization of phenotypic profile of T cells in chronic hepatitis B identifies immune markers predicting HBsAg lossSemantic proximity Read ↗

Association of single nucleotide polymorphisms in immune-related genes with spontaneous HBsAg seroconversion: A systematic review and meta-analysis.Semantic proximity Read ↗

A functional polymorphism in ADAR1 gene affects HBsAg seroclearance both spontaneously and interferon induced.Semantic proximity Read ↗

Genotyping of immune-related loci associated with delayed HBeAg seroconversion in immune-active chronic hepatitis B patients.Semantic proximity Read ↗

HLA-DP polymorphisms affect the outcomes of chronic hepatitis B virus infections, possibly through interacting with viral mutations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.