Article
Higher lifetime chance of spontaneous surface antigen loss in hepatitis B carriers with genotype C infection.
Alimentary pharmacology & therapeutics - 1 May 2015
Tseng T-C, Liu C-J, Chen C-L, Yang W-T, Yang H-C, Su T-H, Wang C-C, Kuo S F-T, Liu C-H, Chen P-J, Chen D-S, Kao J-H
Abstract excerpt
BACKGROUND: Clearance of hepatitis B surface antigen (HBsAg) indicates clinical control of hepatitis B virus (HBV) infection. However, little is known about the impact of viral genomic variations on HBsAg loss. METHODS: We explored the association between viral genomic factors and HBsAg loss in 2121HBeAg-negative patients. HBV pre-core stop codon (1896) and basal core promoter (BCP) (1762/1764) sequences were...
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