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Article

A functional polymorphism in ADAR1 gene affects HBsAg seroclearance both spontaneously and interferon induced.

Liver international : official journal of the International Association for the Study of the Liver - 1 Nov 2014

Wu Xiaopan, Shi Weimei, Wu Jia, Zhu Xilin, Chen Kangmei, Zheng Sujun, Li Zhuo, Duan Zhongping, Li Hui, Liu Ying

Abstract excerpt

BACKGROUND & AIMS: Our previous study found that rs4845384 in ADAR1 gene to be associated with HBeAg seroconversion. However, the effect of rs4845384 on HBsAg seroclearance is unknown. To assess the relationship between rs4845384 and HBsAg seroclearance. METHODS: Two independent case-control studies were conducted to test whether rs4845384 in ADAR1 was associated with HBsAg clearance. Reporter gene assays and...

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Share to Adenosine Deaminase
Share to Alanine Transaminase
Share to Aspartate Aminotransferases
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Share to Hepatitis B, Chronic
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Identifiers

PMID: 24351124
DOI: 10.1111/liv.12444

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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