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Article

Prevalence of somatic mitochondrial mutations and spatial distribution of mitochondria in non-small cell lung cancer.

British journal of cancer - 11 Jul 2017

Kazdal Daniel, Harms Alexander, Endris Volker, Penzel Roland, Kriegsmann Mark, Eichhorn Florian, Muley Thomas, Stenzinger Albrecht, Pfarr Nicole, Weichert Wilko, Warth Arne

Abstract excerpt

BACKGROUND: Mitochondria are considered relevant players in many tumour entities and first data indicate beneficial effects of mitochondria-targeted antioxidants in both cancer prevention and anticancer therapies. To further dissect the potential roles of mitochondria in NSCLC we comprehensively analysed somatic mitochondrial mutations, determined the spatial distribution of mitochondrial DNA within complete...

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Source

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Identifiers

PMID: 28557978
DOI: 10.1038/bjc.2017.155
PMCID: PMC5520508

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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