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Article

Methylation in MAD1L1 is associated with the severity of suicide attempt and phenotypes of depression.

Clinical epigenetics - 4 Jan 2023

Sokolov Aleksandr V, Manu Diana-Maria, Nordberg Didi O T, Boström Adrian D E, Jokinen Jussi, Schiöth Helgi B

Abstract excerpt

Depression is a multifactorial disorder representing a significant public health burden. Previous studies have linked multiple single nucleotide polymorphisms with depressive phenotypes and suicidal behavior. MAD1L1 is a mitosis metaphase checkpoint protein that has been linked to depression in GWAS. Using a longitudinal EWAS approach in an adolescent cohort at two time points (n = 216 and n = 154), we identified...

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Identifiers

PMID: 36600305
DOI: 10.1186/s13148-022-01394-5
PMCID: PMC9811786

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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