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DNA Methylation in Major Depressive Disorder.

Advances in experimental medicine and biology - 1 Jan 2017

Pishva Ehsan, Rutten Bart P F, van den Hove Daniel

Abstract excerpt

Epigenetic mechanisms regulate gene expression, influencing protein levels and ultimately shaping phenotypes during life. However, both stochastic epigenetic variations and environmental reprogramming of the epigenome might influence neurodevelopment and ageing, and this may contribute to the origins of mental ill-health. Studying the role of epigenetic mechanisms is challenging, as genotype-, tissue- and cell...

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PMID: 28523547
DOI: 10.1007/978-3-319-53889-1_10

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