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Article

meQTL and ncRNA functional analyses of 102 GWAS-SNPs associated with depression implicate HACE1 and SHANK2 genes.

Clinical epigenetics - 2 Jul 2020

Ciuculete Diana M, Voisin Sarah, Kular Lara, Jonsson Jörgen, Rask-Andersen Mathias, Mwinyi Jessica, Schiöth Helgi B

Abstract excerpt

BACKGROUND: Little is known about how genetics and epigenetics interplay in depression. Evidence suggests that genetic variants may change vulnerability to depression by modulating DNA methylation (DNAm) and non-coding RNA (ncRNA) levels. Therefore, the aim of the study was to investigate the effect of the genetic variation, previously identified in the largest genome-wide association study for depression, on...

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Identifiers

PMID: 32616021
DOI: 10.1186/s13148-020-00884-8
PMCID: PMC7333393

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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